Abstract：The prediction of preponderant minerogenic series in the eastern section of the Gangdise Mountains, Tibet, is a key problem that needs to be solved currently. The authors studied the provenance characteristics and relations between geochemical targets and minerogenic series, revealed the geochemical constraints of mineralization scale and calculated factors coupling coefficients for predicting potential resources. It can be concluded that four different minerogenic series are concentrated in the eastern section of the Gangdise Mountains.