Abstract：Study of metallogenic conditions of Devonian-Silurian lead-zinc deposits in the Zhenxun (Zhen′an-Xunyang) ore filed shows that Devonian-Silurian lead-zinc deposits in the area generally belong to stratabound deposits. The lead-zinc deposits occur in the Lower Silurian Meiziya Formation, Middle Silurian Shuanghezhen Formation, Middle Devonian Dafenggou Formation and Upper Devonian Nanyangshan Formation. The ore-controlling structures are faults and folds and ore-hosting structures are bedding-parallel fault zones and shear zones; ore-bearing rocks are carbonaceous sandstone, phyllite, limestone, biogenic limestone and dolostone; the sedimentary environments are the shallow-water shelf, tableland margin, lagoon, tidal flat and tableland shallow sea. The Silurian lead-zinc deposits represented by the Sirengou deposit of Xunyang are of fine clastic sedimentary-strongly reworked type; the Devonian lead-zinc deposits represented by the Dalin and Zhaojiagou deposits of Xunyang are of carbonate sedimentary-weakly reworked type and the Devonian lead-zinc deposits represented by the Xitonggou and Yuexi deposits of Zhenan are of carbonate sedimentary-strong reworked type.