Abstract：The Pengshan Sn-polymetallic ore filed is a large Sn-, Pb- and Zn-rich orefield found recently in the Jiujiang-Ruijin area in the middle-lower Yangtze valley. All types of ore deposits are distributed in a halo pattern surrounding the Pengshan buried pluton composed of two-biotite-alkali feldspar granite and biotite monzogranite. The formation of those deposits may be divided into two metallogenic epochs and seven mineralization stages. Analyses of the lead and sulfur isotopic compositions, REE data and fluid inclusions of the Pengshan pluton, typical deposits and country rocks indicate that there is a close relation between the intrusion of late Yanshanian calc-alkaline granite and the formation of polymetallic deposits. The magmatism provided a great deal of ore-forming materials for the Pengshan area.