Abstract：The formation of sedimentary uranium deposits has close relation to organic matter. Experimental simulation study indicates that: aromatic organic acid is very easy to coordinate with uranyl ions under the weakly acid to weakly alkaline conditions and the oxygen atoms of its carboxyl coordinate with uranium atoms in a variety of coordination forms to form coordinate bonds. The results of the experiment simulation validate some previous conclusions and intuitionally exhibit some migration forms of main organic matter functional groups and uranyl ions in solution. The results also show the reduction of hydrocarbon in the formation of uranium deposits under hydrothermal conditions. It can reduce U (Ⅵ) into U (Ⅳ) and deposit the latter.