Abstract：The authors used the hydrocarbon accumulation-forming dynamic system and sandstone-type uranium mineralization dynamic system to analyze the relationship between the mineral deposit (petroleum accumulation) assemblage belt and sedimentary system in which the sandstone-type uranium deposit and petroleum accumulation. They think that it is a common geological phenomenon that repeated migration of hydrocarbon promotes sandstone-type uranium mineralization, which is manifested as follows: primary migration results in preconcentration of uranium mineralization, secondary hydrocarbon migration ends early oxidation zone-type uranium mineralization and seals uranium orebodies in the gray strata, and slight leakage of the petroleum accumulation leads to uranium concentration and mineralization in red sandstone. Furthermore, according to the reduction effect of hydrocarbon on the sandstone-type uranium deposit, the authors have constructed the Tuha-, Dongsheng- and Qianjiadian-type basic models of coexistence of the petroleum accumulation and sandstone-type uranium deposit in the same basin, which enrich the theory on search for sandstone-type uranium deposits and provide reference for comprehensive development and utilization of multiple energy resources.