Abstract：Abundant tin resources are contained in the southern Hunan region. Tin and tin-polymetallic deposits (occurrences) are widespread in the region and their types are complex. Their formation is not only directly related to granitic intrusions but also controlled by factors such as regional strata and geological structure. According to the geological setting, distribution characteristics, deposit features and mineralization characteristics, deposit genesis and ore search information and indicators, the ore search model for tin deposits in the southern Hunan region may be summarized as “delineation of ore belts and ore districts, search for mineralized intrusions and determination of ore deposit locations”. This model not only macroscopically presents or solves the problem of the direction for looking for tin deposits but also has been applied in ore prospecting in recent years, and fruitful results have been achieved in ore finding.