Abstract：With the stable extension of No. 101 and No. 116 ore veins revealed by the prospecting work at depth, the grade of Au has been steadily increased and the Shihu gold deposit has gradually become a large-size gold deposit in the middle of Taihang Mountains. In general, the deposit belongs to a post-magmatic hydrothermal deposit of quartz vein-fault altered rock type, with its ore veins strictly controlled by the fault structure. On the basis of studying the geological setting and analyzing ore-forming lead, sulfur, silicon, carbon, hydrogen and oxygen isotopes and from the new angle of view of the mantle branch structure ore-forming theory, the authors revealed that the ore-forming materials mainly came from the deep part of the earth and the metallogenic solutions were derived mainly from the magmatic water and partly from the atmosphere water. This paper has also discussed the ore-forming process of the Shihu gold deposit, established a metallogenic model for this area, and put forward some suggestions for further prospecting.