Abstract：Huhehu depression is one of the important secondary sags in Hailar Basin, and there exist in this depression two sets of coal-bearing source rocks, namely Damoguaihe Formation and Nantun Formation, which have excellent hydrocarbon-generating conditions and can be regarded as effective coal measure source rocks. Based on a comprehensive evaluation of coal measure source rocks in this depression, the authors calculated the amount of gas generated by the coal measure source rocks by using the approach of basin modeling with the three-dimensional modeling and simulation system. The results show that the coal in the middle and south parts of this depression covers a large area, and the thickness of the coal seam is around 120 meters on average; the kerogen of coal measure source rocks is mainly of type Ⅲ, belonging to gas inclining source rocks; the maturity of the source rocks is mainly at the immature-low mature stage, with Ro mostly between 0.3% and 0.9%. The total amount of coal-formed gas generated is 1.6897×1012 m3 in this depression, which is very favorable for exploration and development.