Abstract：This paper systematically deals with the process of geodynamic evolution in Central Asia and its adjacent areas as well as the regional geology and metallogenic characteristics conditioned by such action, and presents new cognitions and opinions as follows: ① The original Paleo-Asian Ocean zone between Siberian landmass and Sino Korean-Tarim landmass is the special zone of “double-direction accretion” which includes both double-direction side accretion and vertical accretion developed in the same time in the history of geology. ② The “clustered continents of Paleo-China” are independent paleocontinents between Laurasia and Gondwanan. Due to their special location, they form the watershed between Paleo-Asian Ocean and Paleo-Terhys. ③ In the final analysis, the “inter-power” of geodynamics comes from two sources: the first source is the centrifugal force (tension) and extrusion force formed by the rotation and revolution of the earth, constituting the basis of geodynamics. The second source is the eternal “high heat energy bank” in the earth’s interior. The present earthquakes and volcanic activities all result from geological events of the instantaneous change from heat to powerful kinetic energy when the ultrasaturated high heat energy is released from the earth’s surface. ④ These fracture systems with different characteristics caused by the geodynamic system are good ore-controlling and ore deposition space. Hence the “mineral prediction method with fracture system” is one of the simple and effective methods. On such a basis, four test and verification zones of mineral prediction are advanced.