Abstract：The Tuanjiegou gold deposit is a large-size rock gold ore deposit lying in granite- porphyry. As the main ore bodies of this ore deposit have been found in the granite-porphyry, the prospecting and evaluation work in this area has long been mainly carried out within the granite-porphyry. A synthetic analysis and comparative study of the distribution model of REE, the characteristics of sulfur isotope and the temperature of fluid inclusions of the ores and rocks in the ore district and its surrounding areas show that, although the gold deposit is closely related to the granite-porphyry in space, they have no genetic relationship. In this paper, the ore-controlling regularity of the ore deposit is analyzed and summarized systematically, and a new idea is put forward arguing that the structure of the inner circular belt of the volcanic and sub-volcanic edifice is the main ore-controlling structure element. In addition, some favorable ore-prospecting segments in the Tuanjiegou gold orefield are delineated.