Abstract: In this paper Mingnandong pluton was studied throughly by such means as field observation, LA-ICP-MS zircon U-Pb isotopic measurement and petro-geochemistry. The results show that Mingnandong pluton was formed in the Early Jurassic (180.47±0.71Ma). Chemical analyses yielded the following data for Mingnandong pluton: SiO2=60.71%-67.72%, Al2O3=15.60%-17.44%, Na2O+K2O=6.79%-7.63%, K2O/Na2O=0.61-1.01 and A/CNK=0.94-1.01, implying high-potassium calc-alkaline I-type granites. Besides, Mingnandong pluton is enriched in light rare earth elements and large ion lithophile elements, and depleted in heavy rare earth elements and high field strength elements. These features suggest that Mingnandong pluton has obvious characteristics of active continental margin and volcanic arc granites. The ingredient zonation parallel to the orientation of the subduction of oceanic crust made up of cale-alkaine, high-K calc-alkaline granites and the bimodal volcanic rock association from Yanbian and Taiping Mountain to Xiao Hinggan Mountains and Zhangguangcai Mountain indicate the orientation of the subduction of ancient Pacific plate. In a word, the emplacement of Mingnandong pluton was influenced by the subduction of ancient Pacific plate in the Early Jurassic.