Abstract: There are two kinds of physiotherapy geothermal mineral water developed in the northwest of Shandong Province, one referring to carbonate fissure?karst type and the other referring to sandstone fissure?pore type. The carbonate fissure?karst water belongs to Sr·F water, whereas the sandstone fissure?pore water belongs to Sr water and Br·Sr water. According to the analysis of the formation conditions of geothermal mineral water, the authors hold that the weathering crust and karst well?developed buried hill at the top of the Yanggu?Qihe uplift and depression are favorable prospecting target areas for carbonate fissure?karst geothermal mineral water, whereas the secondary structural zones near the deep faults within the North China depression and on the edge of the depression are favorable prospecting target areas for sandstone fissure?pore geothermal mineral water.