Pb, Zn, Sn polymetallic anomalous zones of the Pulao area are situated in the Changshan ore-forming belt in northern Laos. 1:50000 stream sediment geochemical survey identified major anomalies of Pb and Sn, accompanied by other anomalies of Zn, Ag, W, Sb, Bi, As, Hg, Cu and Au. 1:10000 soil geochemical survey delineated 3 comprehensive anomalous zones of Pb, Zn and Sn, which are characterized by high intensity and big size with distinct concentration centers. Test of the anomalies gave rise to 13 Pb, Zn, Sn polymetallic ore spots. Based on study and analysis of geochemical distribution of elements in the anomalous zones and their anomalous features, the authors hold that the polymetallic anomalies are related to mineralization, with potential in search for Pb, Zn, Sn and polymetallic deposits in the area.