Zhuguangshan granitic composite batholith situated in Hunan-Jiangxi-Guangdong border area is an important part of Nanling large granite province, with the total area of northern and southern body being greater than 5000 km². The results of zircon SHRIMP U-Pb geochronology of granitoids of northern Zhuguangshan show that the granitic body was formed in three periods with ages varying from the Caledonian through Indosinian to Yanshannian. Caledonian granodiorite was formed in late Silurian period, Indosinian biotite adamellite was formed in late Triassic period and Yanshannian dimicaceous adamellite was formed in late Jurassic period, with SHRIMP zircon U-Pb ages being (414.5±4.5) Ma, (417.3±4.8) Ma, (207.5±2.7) Ma, and (148.2±1.7) Ma respectively. The results obtained by the authors provide important geochronologic basis for the study of geology and mineralization in this area.