Liulaowan area is located on the northern piedmont of the Dabie orogenic belt in Henan Province, neighboring MeishanGuishan regional fault in the south and the Yanshanian Shangcheng granite body in the west. Geochemical anomalies dominated by Au, Ag, Cu, Pb, Zn were delineated on the basis of 1:50000 stream sediment survey. The Au geochemical anomalies are large in size, and have obvious concentration centers and good element combinations. High-value magnetic anomalies are consistent with the geochemical anomalies. The authors carried out anomaly verification work through measuring the geological, geophysical and geochemical prospecting sections. The authors delineated multiple high-value Au soil anomalies, accompanied by highly intensified and low resistance anomalies. In this paper, based on the detailed and contrastive analysis of the geological, geophysical and geochemical anomalies as well as metallogenic conditions in the area,consider that the favorable parts of prospecting are contact zone of intermediate-acid pluton and Huyoufang Formation, NWW faults structural; there are better prospecting potential in the zones of Au high-anomaly, the part of the mutation of positive and negative magnetic anomaly, the high polarizability and the low resistivity.