This dataset contains information about location, sampling horizon and 35-inorganicgeochemical-component testing results for 742 groundwater samples collected in Ordos Basin during 2014 and 2015. The sampling process for this dataset has been normalized while testing results have been obtained through a qualified laboratory. The data presented herein is reliable and truly reflects the quality of groundwater in Ordos Basin during the aforementioned period. All in all, this dataset provides geochemical indicator reference for studying circulation and evolution of groundwater in Ordos Basin.