This paper describes the collection of measured and tested data of 18 elements (Au, Cu, Zn, As, Sb, Hg, Bi, Ti, V, Ag, Sn, Pb, W, Mo, Ni, Co, Cr and Cd) in the stream sediments of seven 1:50 000 map sheets in the integrated survey area of the Shiquan-Xunyang gold ore zone, Shaanxi, including 13 169 data points and 180 944 total pieces of data, and the establishment of a geochemical database in the survey area for the first time. Building on this, 233 sheets of a variety of geochemical maps are developed and a spatial database established. Within the database, 2 083 places of various single-element anomalies are delineated in the area, including 304 Au anomalies; 10 Au prospecting target areas and 12 Au prospective areas are delineated; with subsequent comprehensive checking of minerals throughout the integrated survey area, there are 53 Au deposits (points), including 8 medium-scale Au deposits and 18 small-scale ones, indicating that Au anomalies correspond well with Au deposits (points), and there are 189 places of mineralized anomalies, indicating that the measurement of 1:50 000 stream sediments is one of the best means of prospecting in the survey area.