This paper is the result of monitoring and evaluating engineering of natural resources.
[Objective] As a new expansion business of China Geological Survey in 2021, the comprehensive survey of natural resources aims to serve land and space planning, use control and ecological protection and restoration. [Methods] Based on the monitoring data of land use/cover change in the watershed in 2000, 2010, and 2020, ArcGIS software was used to analyze the spatiotemporal changes in land use types and ecological space of Weihe River Basin. [Results] The results show that:1) during 2000-2010, 804.4 km², 350.3 km² and 327.6 km² of cropland converted into grassland, forest and constructive land respectively, while only 94.3 km² grassland, 10.4 km² forest and 1.2 km² constructive land converted into cropland; 2) during 2010-2020, 16646.8 km², 3024.5 km² and 2547.9 km² of cropland converted into grassland, forest and constructive land respectively, while 16867.7 km² grassland, 3103.6 km² forest and 2528.82 km² constructive land converted into cropland; 3) during 2000-2020, the conversion of ecological space land in this region reaches 48,165 km², of which the ecological→semi-ecological land was 20172 km², the semi-ecological→ecological land was 20,897 km², the weak ecological→semi-ecological land was 2,519 km², and the semi-ecological→weak ecological land was 2754 km². It reflects that the conversion of ecological space land in the region tends to balance and the quality of the ecosystem is slowly increasing. [Conclusions] The results is of great significance for accelerating comprehensive regionalization of natural resources and optimizes "three-zone and the-lines" of the Territorial Spatial Plan in the Weihe River Basin.