Abstract: The integrated application of existing borehole data has become an urgent need with further prospecting of sandstone-hosted uranium deposits. In this paper, a comprehensive borehole database of Jurassic–Cretaceous strata in Dongsheng area (also referred to as the Database) was established under the guidance of the new ideas and methods of “secondary development and utilization of existing coalfield borehole data” and “coal-uranium joint exploration”. In detail, the borehole attributes of Dongsheng area were collected. Then key borehole data related to coalfields and uranium deposits were successively collated, scanned, converted into desired data types, input into data tables, and integrated into databases according to unified standards and requirements. As a result, the Database was established, achieving unified management of borehole data from multiple sources. The Database consists of three Access databases and corresponding result maps. Each of the Access databases contains eight data tables, namely Basic information of a borehole, Beds based on comprehensive histograms, Beds based on lithologic description, Names and codes of strata, Data from logging curves, Configuration of logging curves, Bending degree measurement of boreholes, etc. These data tables respectively contain detailed data of the lithology from geologic records, beds, rock colors, logging curves, hydrogeological beds, borehole sampling, and bending degree measurement. According to application and practices, the Database enables a quick generation of critical basic geologic maps such as well profiles and the isoline maps of the elevations of roofs and floors, stratum thickness, sand-body thickness, and sand content of target strata bearing coal and uranium. This will increase the data utilization efficiency and provide critical data for the exploration and research of uranium deposits.