Abstract：Based on data from such disciplines as sedimentology, coal geology, sequence stratigraphy and paleontology, the authors studied the sequence statigraphy, the relative sea-level fluctuation and its response to sequence stratigraphy. The results show that there are eight sequence surfaces, which mainly include palaeostructural surface, palaeontologic gap surface, large-area peat-moor surface, low stand floor surface of continental sea, transpressional basin surface, large-area buried erosion surface, large-area exposed surface, and siliceous spongolite surface. According to the principle of sequence stratigraphy division, the authors recognized one basin filling sequence, three tectonic sequences (second-grade sequences) and seven third-grade sequences. Two stages of relative sea level can be found based on the sequence stratigraphy framework. The first stage is from sequence 1 to sequence 3, which is composed of a short-time transgression and a long-time regression. The second stage is from sequence 4 to sequence 7, which is a long-time regression. On such a basis, the authors hold that the sea-level change of North China in Late Paleozoic can be studied by the sea-level curved shape and its response to sequence stratigraphy. The first characteristic is periodicity and compounding, and the second characteristic is high frequency and event synchronization.