Abstract: Analysis of static geological elements of petroleum combinations in the Lile basin indicates that there are three suites of source rock in the Lile basin, i.e. lower Oligocene, Paleocene to Miocene and Mesozoic, of which the second and third suites have better hydrocarbon-generating potential. Sandstone, carbonate rocks and organic reefs are the main reservoir types, of which the sandstone reservoir is widely developed in the Meso-Cenozoic strata, while the carbonate and organic reef reservoirs are mainly developed in the upper Oligocene to Quaternary. Generally, the basin is lacking in widespread regional cap rocks with good sealing properties, but locally the cap rocks are well developed and have good sealing properties.. There are three petroleum-bearing combinations in this basin, i.e. the Mesozoic, Paleogene and Neogene petroleum-bearing combinations. The Mesozoic one has good oil-gas prospects; the Paleogene one is the most important exploration target in the basin and has the best prospect; and for the Neogene one, it is possibly difficult to form a good petroleum combination in the uplift in the central part of the basin, whereas in the depressions of the basin, especially in the southern depression, a good petroleum combination may be formed.