Abstract：In order to improve the application effect of metallogenic regularity in prospecting analysis and mineral prospecting, the authors adopted three steps for exploration work in Huangshan-Jing’erquan area of Xinjiang, The three steps are as follows： (1) the detailed summarization of critical mineral process; (2) the determination of geological factors; (3) the extraction of geological factors from geological, geophysical, geochemical and remote sensing data. These steps help to convert the metallogenic regularity into geological factors by linking the genesis and distribution of ore deposits in space and time to regional geology, geophysics, geochemistry and remote sensing. 13 prospective areas such as Huangshan and Tula’ergen were delineated by using characteristic analysis to study geological factors. The results obtained by the authors indicate the direction for future Ni exploration.