The 1∶50 000 mineral and geological map of Zangjiazhuang Map-sheet (J51E016004), Shandong Province was prepared according to applicable industry standards such as Technical Requirement of 1∶50 000 Solid Mineral Geological Survey (DD 2019-02) and Spatial Database for Digital Geological Map (DD 2006-06), during which the results of relevant 1∶50 000- and 1∶200 000-scale regional geological surveys were fully adopted. In addition, a digital mapping system was applied to acquire data in the field, and indoor map preparation was conducted in combination with field survey of key survey sites. The data in the 1∶50 000 mineral and geological map database of Zangjiazhuang Map-sheet, Shandong Province (also referred to as the Database) was individually stored according to four types of classes, namely feature classes, complex classes, object classes and independent feature classes. In this paper, a new polymetallic metallogenic belt located in Qixia, Yantai City was proposed, i.e., the Gaojia–Xiangkuang–Xingjiashan polymetallic metallogenic belt. This metallogenic belt, with Mesozoic acid intrusions as metallogenic intrusions, is under the control of the intersection of the EW- and NNE-trending faults. LA-ICP-MS zircon U-Pb dating of the metallogenic intrusions in typical Xiangkuang polymetallic deposits indicates that the metallogenic age of the metallogenic intrusions is 127.91±0.58 Ma, providing new credible data for research into the metallogenic ages and rules of the polymetallic deposits in Zangjiazhuang Map-sheet. The Database covers the data of five ages and 25 mineral deposits, including two copper ore occurrences and one gold mineralized point that were newly discovered. Meanwhile, two prospecting target areas were determined and six predicted minimum prospecting target areas were delineated. Furthermore, the resources of Au, Ag, Pb and Zn in the new polymetallic metallogenic belt were predicted to be 10 962 kg, 499.638 t, 141 437 t and 230 011 t, respectively. The Database could provide basic data for the geological prospecting in Zangjiazhuang Map-sheet, as well as data sources for information- and network-oriented construction of geology.