The 1∶50 000 mineral geological map of the Huangzhuguan Map-sheet, Gansu (I47E013015) is compiled in accordance with the Technical Requirements of Solid Mineral Geological Survey (DD 2019–02) and unified industrial standards and requirements. On the basis of existing 1∶50 000 and 1∶250 000 regional geological survey results, the work was performed through field geology-specific mapping both outdoors and indoors with the help of digital mapping systems. The Huangzhuguang mineral geological map redivides the formation types of the Devonian Xihanshui Group, and establishes three formation units of the Devonian lead and zinc-forming period, including lead-zinc-bearing carbonate rock formation (D₁a^1a), lead-zinc-rich carbonate rock formation (D₁a^1c), and lead-zinc-poor phyllite with limestone formation (D₁a²). The map also establishes the EW fold–fault structure systems within the map-sheet area, highlights the lead-zinc ore-bearing formations and the special lithologic layers closely related to the metallogenesis of lead and zinc, and innovatively presents geological features related to the metallogenesis of lead and zinc in the exhalation sedimentation period and hydrothermal reformation period supplemented by a lithofacies paleogeographic sketch map and a tectonic outline map. The database contains 16 stratigraphic units, five stages of intrusive rocks, three stages of structures, four isotopic ages, 12 pieces of whole-rock analytical data, and 30 pieces of mineral deposit data, with a data volume of 30.6 MB. The database gives a full presentation of the demonstrative results of 1∶50 000 mineral geological survey and can provide reference for other similar areas.