The 1∶50 000 mineral geological map database of the Panxin Map-sheet (H49E024005) of the Songtao manganese deposit in Tongren, Guizhou represents one of the achievements of the new round of 1∶50 000 mineral geological survey work series in accordance with the Technical Requirements for Mineral Geological Survey (1∶50 000) (DD2019-02) initiated by the China Geological Survey (CGS). The work reviews the lithostratigraphic sequence of the Panxin Map-sheet surveying area, determines 39 mapping units, identified eight formation types, and emphatically divides five genetically interrelated manganese-bearing formation mapping units. The database is built in MapGIS format. It mainly includes geographic layers, formation-structure layers, mineral deposit layers, and finishing layers, covering 150 pieces of rock geochemical analysis data, 333 pieces of general rock and ore analysis data, 90 pieces of zircon U–Pb age data, 6 pieces of mineral deposit information, and two deposit types. The database highlights ore-bearing formation, ore-controlling structure and mineralization alteration information, providing base data for manganese-related resource research, energy exploration, and mineral resource planning.